What is Chronic Inflammation? How do You Reduce It?

Inflammation is a normal immune process that occurs in response to an infection or injury.

Chronic inflammation occurs when acute inflammation doesn’t shut off. Often, there are factors that keep driving inflammation, including prolonged exposure to the cause of inflammation or an inappropriate reaction of the immune system against the body’s own tissue. The result is lower levels of inflammation that may go undetected but lead to consequences on cells, tissues and organs.

There are many sources and drivers of chronic inflammation, especially in today’s world. Here are some of the most common factors that keep the inflammation switch flipped on:

Toxins – chemicals in food, plastics, mold toxins, pesticides, particulates, vaccines and other chemicals you may be daily exposed to.
Food allergy/sensitivities – High inflammatory foods like gluten, dairy, sugar, processed foods, GMO foods, and foods with a known allergy can all cause inflammation for many.
Elevated blood sugar – High blood sugar is inflammatory.
Stress – Stress plays a role in inflammation. Cortisol, a main hormone for circadian rhythm is actually anti-inflammatory. It’s possible that with chronic stress or HPA-axis dysfunction, cortisol levels are low, causing inflammation to rise.
Infections – Gut infections such as bacterial infections, SIBO, yeast overgrowth and parasites are a common source of inflammation. Chronic viral infections, such as Epstein-Barr virus and post-COVID syndrome.
Excess weight – Excess fat not only affects metabolic health but correlates with higher levels of inflammation in the body. Obesity is considered a state of low-grade systemic inflammation.

Read about the benefits of implementing a low inflammatory diet here and here.

Supportive supplements

Inflammatory Markers:

The following labs are indicators of inflammation in the body. Inflammation may be caused by a bacterial or viral infection, food or environmental allergies, toxins, injury, disease or an autoimmune condition.

High Sensitivity C-Reactive Protein (hs-CRP) CRP is an acute phase inflammatory plasma protein synthesized by the liver. The “high sensitivity” CRP test is needed to detect very low levels of CRP that may be seen with vascular and/or systemic inflammation.
An erythrocyte sedimentation rate (ESR) is a type of blood test that measures how quickly erythrocytes, or red blood cells, settle to the bottom of a test tube blood sample. A faster-than-normal rate may indicate inflammation in the body.
Myeloperoxidase MPO (Quest, or Boston Heart) The MPO Blood Test measures the antibody levels of Myeloperoxidase. Elevated Myeloperoxidase antibodies are associated with vascular diseases, or other inflammatory conditions.
Lipoprotein-Associated Phospholipase A2 Activity [LpPLA2] (Quest or Boston Heart) The Lp-PLA2 test is associated with vascular inflammation, and high levels are thought to increase the chance of cardiovascular events, including heart attack or stroke.
Ferritin is a key mediator of immune dysregulation, especially under extreme hyperferritinemia, via direct immune-suppressive and pro-inflammatory effects, contributing to the cytokine storm.
Fibrinogen levels may rise sharply during any condition that causes inflammation or tissue damage.
PULS (Protein Unstable Lesion Signature) Cardiac Test is a simple blood test that measures the body’s immune system response to arterial injury. Injuries that lead to the formation and progression of cardiac lesions which may become unstable and rupture, leading to cardiac event. Read more here.

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